The non-surgical side of cosmetic medicine has transformed dramatically over the past two decades — what was once a narrow category dominated by a handful of injectables has expanded into a comprehensive set of treatments capable of producing meaningful facial rejuvenation, body refinement, and skin restoration without surgery. Today, properly chosen and skillfully administered non-surgical treatments — Botox, Dysport, Xeomin, hyaluronic acid fillers, biostimulatory injectables, fat-dissolving injections, and chemical peels — produce results that rival what was previously achievable only through more invasive procedures. The choice of which treatment fits which patient, which product fits which anatomical area, and which combinations produce the most natural-looking result requires the judgment of a board-certified plastic surgeon — not a technician. Dr. John Anastasatos at Los Angeles Plastic Surgery offers a comprehensive portfolio of non-surgical cosmetic treatments at his Beverly Hills office, with every injection and treatment performed personally rather than delegated.

Dr. Anastasatos brings the most directly relevant academic credential possible to non-surgical injectable and skin treatment: he has delivered formal academic lectures at the UAB Kirklin Clinic on “Botox and Chemical Peels” — the foundational injectable and topical treatments in modern facial rejuvenation. He has published peer-reviewed academic work on Cell-Assisted Lipotransfer (CAL) — directly relevant to the science of volume restoration that underlies modern dermal filler science. He was profiled by the Beverly Hills Courier in a feature titled “Anastasatos turns Body Restoration into art form.” He has been an invited lecturer at the Royal Society of Medicine in London on advanced facial aesthetic surgical techniques, with an invited 2026 return as featured speaker. With over two decades of facial and body cosmetic surgical expertise in Beverly Hills since 2007, he is board certified by the American Board of Plastic Surgery, a Fellow of the American College of Surgeons (FACS), a member of the American Society of Plastic Surgeons (ASPS) and American Society for Aesthetic Plastic Surgery (ASAPS), and named by The Luxe Insider as one of the Top 10 Plastic Surgeons in the World.

Our Non-Surgical Treatment Options

The following non-surgical cosmetic treatments are available at our Beverly Hills office:

Understanding Hyaluronic Acid Fillers

Hyaluronic acid is a naturally occurring sugar found in all mammals — a substance present throughout human tissue that delivers nutrients, hydrates skin by holding water, and acts as a natural cushioning agent. Modern injectable hyaluronic acid fillers leverage this biology to restore facial volume safely and predictably.

What is less commonly understood is the second mechanism that makes these fillers durable. Injectable hyaluronic acid is gradually dissolved by an enzyme called hyaluronidase. As the filler resorbs, the body fills the space with newly formed collagen — and this new collagen acts as a permanent volumizer that extends well beyond the duration of the original filler. The combination of immediate filler effect plus collagen-driven extended volume is what produces the lasting outcomes refined dermal filler treatment is known for.

Modern hyaluronic acid fillers are produced through bacterial fermentation rather than from animal tissue — a synthetic, non-animal-derived production method that meaningfully reduces the risk of allergic reaction or immune response. True autoimmune responses against modern hyaluronic acid fillers have not been supported in the medical literature.

Filler Selection by Anatomical Area

Dr. Anastasatos’s clinical approach matches specific filler products to specific anatomical concerns. The selection logic is consistent across every patient:

• Cheek Augmentation and Lifting: Juvéderm Voluma and Radiesse — Voluma for sculpted cheekbone definition with effects typically lasting approximately 18 months; Radiesse for stronger volumizing where deeper structural support is needed
• Jawline Augmentation: Radiesse, Juvéderm Voluma, and Juvéderm Volux — biostimulatory and dense hyaluronic acid fillers that produce angular definition along the jawline
• Chin Augmentation: Juvéderm Voluma and Juvéderm Volux — for projecting and refining the chin without surgery
• Hand Rejuvenation: Radiesse — restoring lost volume on the dorsum of the hand to reduce visible tendons and veins
• Facial Lines and Wrinkles: Juvéderm and Restylane product families — including specialized variants for delicate areas (Restylane Silk, Juvéderm Volbella) and deeper folds (Restylane Lyft, Juvéderm Vollure)

Each product family has specific characteristics — particle size, viscosity, cross-linking, longevity — that make it appropriate for particular indications. The art is in matching the right filler to the right depth, the right anatomical area, and the right patient.

When Antibody Formation Affects Filler Effectiveness

A small subset of patients develop antibodies against synthetic hyaluronic acid material with repeated treatments, which can reduce the effectiveness of subsequent injections. The clinical significance of these antibodies remains under investigation, but in patients where this becomes a practical issue, micro fat transfer is an excellent alternative — the patient’s own fat, harvested through small liposuction and processed for facial transfer, produces volume restoration without the antibody concern.

Beyond Hyaluronic Acid Fillers

The non-surgical portfolio extends well beyond hyaluronic acid:

• Neuromodulators (Botox, Dysport, Xeomin): Address dynamic wrinkles — the lines that appear with facial expression — by selectively relaxing the underlying muscles that produce them
• Biostimulatory Fillers (Sculptra, Radiesse): Stimulate the body’s own collagen production for gradual, longer-lasting volume restoration
• Fat-Dissolving Injections (Kybella): Dissolve submental fat under the chin without surgery
• Reversal Agent (Hyaluronidase): Available to dissolve hyaluronic acid filler when correction or refinement is needed
• Skin Resurfacing (Chemical Peels, Dermabrasion): Address surface texture, pigmentation, and fine lines through controlled exfoliation and resurfacing

Schedule a Non-Surgical Treatment Consultation in Beverly Hills

Whether you are considering your first non-surgical treatment or refining a long-running rejuvenation plan, having every injection and skin procedure performed personally by a board-certified plastic surgeon meaningfully shapes the result. Dr. John Anastasatos welcomes patients to the Beverly Hills office at 436 North Bedford Drive, Suite 202, Beverly Hills, CA 90210, for a private consultation. Contact Los Angeles Plastic Surgery to schedule your appointment with Dr. Anastasatos.