Xeomin is a precision neuromodulator that effectively treats the dynamic wrinkles produced by repeated facial expression — the vertical “11” frown lines between the eyebrows, horizontal forehead creases, and crow’s feet that radiate from the corners of the eyes. Like Botox and Dysport, Xeomin is a botulinum toxin type A formulation that temporarily relaxes specific facial muscles to smooth the wrinkles their contraction produces. What distinguishes Xeomin is its formulation: it is sometimes called “naked” Botox because it contains no complexing proteins — just the active botulinum toxin alone. This purified formulation may reduce the risk of antibody formation that can, in rare patients, blunt the effectiveness of repeated neuromodulator treatments over time. For patients who have used Botox or Dysport for years and noticed diminishing duration, switching to Xeomin can sometimes restore the original responsiveness. Dr. John Anastasatos at Los Angeles Plastic Surgery offers Xeomin injections at his Beverly Hills office — performed personally by a board-certified plastic surgeon, not delegated to a technician.

Dr. Anastasatos brings the most directly relevant academic credential possible to Xeomin treatment: he has delivered formal academic lectures at the UAB Kirklin Clinic on “Botox and Chemical Peels” — direct teaching credentials in injectable neuromodulator treatment that apply equally to Xeomin. With over two decades of facial cosmetic expertise in Beverly Hills since 2007, he is board certified by the American Board of Plastic Surgery, a Fellow of the American College of Surgeons (FACS), a member of the American Society of Plastic Surgeons (ASPS) and American Society for Aesthetic Plastic Surgery (ASAPS), and named by The Luxe Insider as one of the Top 10 Plastic Surgeons in the World.

How Xeomin Works

Xeomin (incobotulinumtoxinA) is a botulinum toxin type A — the same general mechanism as Botox and Dysport. When injected into a specific facial muscle, Xeomin temporarily blocks the release of acetylcholine, the neurotransmitter that signals the muscle to contract. With contraction blocked, the muscle relaxes, and the wrinkle produced by its repeated movement smooths as the overlying skin relaxes.

The treated muscles relax. The surrounding muscles continue to function normally. Facial expression remains natural — patients still smile, frown, raise their eyebrows, and convey emotion fully.

What Distinguishes Xeomin

The key differentiator is purity. While Botox contains the active botulinum toxin protein along with surrounding complexing proteins, Xeomin contains only the active toxin itself — a purified formulation that some clinicians refer to as “naked” Botox. The clinical implications include:

• Reduced antibody formation potential — In a small subset of long-term neuromodulator patients, the body may form antibodies that blunt effectiveness; Xeomin’s purified formulation may reduce this risk
• Switching option for patients with diminishing Botox response — Patients who have used Botox for years and noticed shorter duration may regain effectiveness with Xeomin
• Preservative-free formulation — Xeomin does not contain human albumin, which may be relevant for patients with specific sensitivities

For patients newly considering neuromodulator treatment, Xeomin, Botox, and Dysport produce comparable cosmetic results — choice between them is influenced by anatomical area, patient response history, and clinician preference.

Areas of the Face Xeomin Treats Best

Xeomin is FDA-approved for moderate-to-severe glabellar lines and is widely used for additional indications in trained hands:

• Frown Lines (Glabellar Lines): The vertical “11” lines between the eyebrows — Xeomin’s primary FDA-approved cosmetic indication
• Forehead Lines: Horizontal lines across the forehead from raising the eyebrows
• Crow’s Feet: Fine lines radiating from the corners of the eyes
• Bunny Lines: Diagonal wrinkles along the sides of the nose when scrunching
• Subtle Brow Lift: Strategic placement can elevate the eyebrows by relaxing the muscles that pull them downward
• Perioral Lines: Vertical lines around the mouth — a refined application requiring careful dosing
• Masseter Reduction: Some patients respond better to Xeomin than other neuromodulators for jaw slimming

What to Expect From a Xeomin Treatment

• 15-minute office visit — Quick treatment that fits into a lunch break
• No downtime — Patients return to normal activities immediately
• Onset: 3 to 5 days for visible improvement; full effect by 7 to 14 days
• Duration: Typically 3 to 4 months
• Maintenance schedule: Repeat treatment every 3 to 4 months for consistent results
• Mild swelling, redness, or pinpoint bruising — Possible at injection sites; typically resolves within 24 to 48 hours

Why Choose Dr. Anastasatos for Xeomin Treatment

• UAB Kirklin Clinic Lecturer on Injectables: Direct academic teaching credentials in injectable neuromodulator treatment
• Two Decades in Beverly Hills: Private practice since 2007 dedicated to facial cosmetic surgery and rejuvenation
• Performed Personally: Every Xeomin injection performed by Dr. Anastasatos
• Comprehensive Neuromodulator Experience: Botox, Dysport, and Xeomin — selecting the right product for each patient and indication
• Comprehensive Facial Anatomy Expertise: Plastic surgical training informs precise dosing and placement
• Top 10 Plastic Surgeon in the World: Named by The Luxe Insider

Schedule Your Xeomin Consultation in Beverly Hills

If forehead lines, frown lines, or crow’s feet are showing more than the rest of your face suggests — or if your previous Botox treatments have produced diminishing results — Xeomin offers a refined, purified alternative performed by a board-certified plastic surgeon. Dr. John Anastasatos welcomes patients to the Beverly Hills office at 436 North Bedford Drive, Suite 202, Beverly Hills, CA 90210, for a private consultation or treatment. Contact Los Angeles Plastic Surgery to schedule your appointment with Dr. Anastasatos.